Case Report

Year : 2021 | Volume : 5 | Issue : 2 | Page : 70 - 73

Recurrent metastatic malignant granular cell tumor of the back presenting with axillary mass: A rare case report and review of the literature

Kavita Mardi, Pooja Murgai, Priyanka Mehta, Monica Sarohi

Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

Address for correspondence:

Dr. Kavita Mardi, Set No 14, Type VI Quarters, IAS Colony, Mehle, Shimla, Himachal Pradesh, India.

E‐mail: kavitamardi@yahoo.co.in

Abstract

Malignant granular cell tumor (MGCT) is a rare aggressive tumor that comprises 0.5%–2% of all granular cell tumors. They most commonly occur on lower extremity, nuchal region, chest wall, gastrointestinal tract, and head and neck. We report fine needle aspiration and histopathological findings of a rare case of recurrent MGCT presenting with axillary mass along with a tumor on the right back in a 56-year-old female. Tumor cells with abundant granular eosinophilic cytoplasm showing pleomorphism, enlarged vesicular nuclei, prominent nucleoli, 4–5 mitotic figures/10 high-power field, periodic acid– Schiff-positive diastase-resistant cytoplasmic granules, and metastasis in the axillary lymph node were also suggestive of MGCT. Immunohistochemically, the tumor cells were positive for S-100 confirming the diagnosis.

Keywords: Fine needle aspiration cytology, granular cell tumor, malignant

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Conflicts of interest

There are no conflicts of interest.

How to cite this article:

Mardi K, Murgai P, Mehta P, Sarohi M. Recurrent metastatic malignant granular cell tumor of the back presenting with axillary mass: A rare case report and review of the literature. Int J Clinicopathol Correl 2021;5:70-3.