Case Report

Year : 2019 | Volume : 3 | Issue : 1 | Page : 32 - 35

C1q nephropathy in a young female sensitive to low‐dose steroid: Clinicopathological correlation and outcome a rare clinical scenario

Rajesh Kumar, Amit Kumar Singh, Yasir S. Rizvi1, Rajan Duggal2

Department of Nephrology and Renal Transplant Medicine, VMMC and Safdarjung Hospital, 1 Senior Consultant Nephrologist, Dharamshila Narayana Superspeciality Hospital, New Delhi, 2 Department of Nephropathology, NephroCore, Gurugram, Haryana, India

Address for correspondence:

Dr. Rajesh Kumar, Department of Nephrology and Renal Transplant Medicine, VMMC and Safdarjung Hospital, New Delhi ‐ 110 029, India.

E‐mail: drrajeshkumar80@yahoo.com

Abstract

C1q nephropathy is a very uncommon form of glomerular disease and the presentation usually coincide with nephrotic syndrome. The histological patterns of C1q nephropathy broadly divided into minimal change disease, focal segmental glomerulosclerosis, and immune‐mediated proliferative glomerulosclerosis. Here, we are presenting an interesting case of C1q nephropathy in young female who achieved complete remission on low‐dose corticosteroid therapy. Corticosteroids, according to the body weight, are the mainstay of treatment. Some patients who do not tolerate, a low dose of steroid may be used. It is found to be resistant in most of the cases and other immunosuppressant is reserved for such cases.

Keywords: C1q nephropathy, complement system, focal segmental glomerulosclerosis, minimal change disease, systemic lupus erythematosus

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

How to cite this article:

Kumar R, Singh AK, Rizvi YS, Duggal R. C1q nephropathy in a young female sensitive to low-dose steroid: Clinicopathological correlation and outcome a rare clinical scenario. Int J Clinicopathol Correl 2019;3:32-5.

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