Case Report
Year : 2017 | Volume : 1 | Issue : 2 | Page : 54 - 60
Osteolytic lesion of the mandible in a 42‐year‐old female
Jeffrey Allan Elo1,2, Ho‐Hyun Brian Sun3, Chan M. Park3,4 1
Division of Oral and Maxillofacial Surgery, College of Dental Medicine, Western University of Health Sciences, Pomona, 2 Department of Oral and Maxillofacial Surgery, Loma Linda University Medical Center, Loma Linda, 3 Division of Oral and Maxillofacial Surgery, Alameda Health System, Highland Hospital, Oakland, 4 Department of Oral and Maxillofacial Surgery, Dugoni School of Dentistry, University of the Pacific, San Francisco, CA, USA
Address for correspondence:
Dr. Jeffrey Allan Elo, Division of Oral and Maxillofacial Surgery, College of Dental Medicine, Western University of Health Sciences, 795 E. Second St., 3rd Floor, Pomona, CA 91766, USA.
E‐mail: jelo@westernu.edu
Abstract
A case of metastatic breast cancer with medication‐related osteonecrosis of the jaws is described in a 42‐year‐old Hispanic female who was previously unaware of a preexisting breast carcinoma. Radiographic examination demonstrated the absence of visible lamina dura and periodontal ligament on teeth in the affected area; while clinical examination demonstrated a moderately diffuse swelling of the right mandible and vestibule without distinct masses. Microscopy revealed disordered lesional cells with moderate variations in nuclear size, shape, and chromaticity, with a low mitotic index. Also noted were segments of necrotic remodeled resorbed lamellar bone showing enlarged empty osteocytic lacunae, a serrated external surface, adherent granular basophilic bacteria, and a fibrinous exudate with neutrophils.
Keywords: Mandibular metastases, medication‐related osteonecrosis of the jaw, medication‐related osteonecrosis of the jaw, metastatic breast cancer, numb chin
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
How to cite this article:
Elo JA, Sun HHB, Park CM. Osteolytic lesion of the mandible in a 42-year-old female. Int J Clinicopathol Correl 2017;1:54-60.
