Review Article

Year : 2024 | Volume : 13 | Issue : 1 | Page : 6-10

Unraveling The Impact: Mast Cells In Oral Pathology

Pallavi Yaduka 1, Trivandrum Anandapadmanabhan Lakshmi 2

1,2-GeneralPractitioner,Chennai

Address for Correspondence:

Trivandrum Anandapadmanabhan Lakshmi

General Practitioner, Chennai

Email:drlakshmi.ta@gmail.com

ABSTRACT

Mast cells play a crucial role in the immune response, particularly in allergic reactions and inflammatory processes. In the context of oral diseases, mast cells have been implicated in various pathological conditions, including gingivitis, periodontitis, oral lichen planus, and oral cancer. This comprehensive review aims to explore the role of mast cells in the pathogenesis of these oral diseases, focusing on their activation, degranulation, and subsequent release of mediators such as histamine, cytokines, and growth factors. Furthermore, this review discusses the interaction between mast cells and other immune cells, as well as their involvement in angiogenesis, tissue remodelling, and pain modulation in the oral cavity. A thorough understanding of the role of mast cells in oral diseases may pave the way for the development of novel therapeutic strategies targeting mast cell activation and function, ultimately improving the management of these conditions.

Keywords: allergy, cytokines, pulpitis, fibrosis, mast cells

FUNDING INFORMATION

Nil

CONFLICT OF INTEREST

Nil

How to Cite this article: Yaduka, P., & Trivandrum Anandapadmanabhan, L. (2024). Unraveling The Impact: Mast Cells In Oral Pathology: Review Article. International Journal of Histopathological Interpretation, 13(1), 6–10. https://doi.org/10.56501/intjhistopatholinterpret.v13i1.1041