Original Article
Year : 2017 | Volume : 6 | Issue : 1 | Page : 1-4
Cytomorphometric Analysis of Exfoliated Buccal Mucosal Cells in Smokers and Tobacco Chewers
Abhishek Singh Nayyar, B. Kartheeki, Pallavi Sinha, Kazi Abdullah Zakaria1 , Channe Rashmi Chandrakant1 , Abhay Kulkarni
Department of Oral Medicine and Radiology, SaraswatiDhanwantari Dental College and Hospital and PostGraduate Research Institute, Parbhani, 1 Department of Oral Medicine and Radiology, Pandit Deendayal Upadhyay Dental College and Hospital, Solapur, Maharashtra, India
Address for correspondence:
Dr. Abhishek Singh Nayyar, Department of Oral Medicine and Radiology, Saraswati Dhanwantari Dental College and Hospital, Post‑Graduate Research Institute, Parbhani ‑ 431 401, Maharashtra, India. E‑mail: singhabhishekndls@gmail.com
Abstract
Aims and Objectives:
Exfoliative cytology is a minimally invasive procedure that has been used for the detection of early changes in clinically normal oral mucosa of tobacco users. This study highlights the cause‑effect relationship between tobacco usage in varied forms and the structural cellular and nuclear alterations in different age groups.
Materials and Methods:
This study was conducted with different age groups who were tobacco users as a planned, cross‑sectional study.
Results:
The results of the study revealed that the mean nuclear diameter (ND) and cytoplasmic diameter (CD) showed a statistically significant difference in the control group and in smokers and tobacco chewers.
Conclusion:
Increase in ND and decreased CD, as well as an altered nucleo‑cytoplasmic ratio, appear to be due to chronic tobacco usage and cytomorphometric analysis can be used to detect these cellular and subcellular alterations at an early enough stage before actually a frank, morphological change can be appreciated in relation to the oral mucosa.
Keywords: Cytomorphometry, oral mucosa, tobacco
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
How to cite this article:
Nayyar AS, Kartheeki B, Sinha P, Zakaria KA, Chandrakant CR, Kulkarni A. Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers. Int J Histopathol Interpret 2017;6:1-4.
