Case Report

Year : 2022 | Volume : 11 | Issue : 2 | Page : 15-19

Extra Skeletal Myxoid Chondrosarcomaof Hand–A Case Report with Review of Literature

Shamaila Sameen 1 , Siddiqui Bushra 2 , Alam Feroz 3 , Nahid Zeeshan 4

1,2,3,4, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India – 202002.

Address for Correspondence:

Shamaila Sameen,

Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India. 202002 Phone: 8755735833,

Email: shamailasameen@gmail.com

Abstract

Extraskeletal myxoid chondrosarcoma (EMC) arising from soft tissues is a rare neoplasm morphologically characterized by ill-defined nodular masses composed of cords and strands of small eosinophilic cells separated by fibrous septae along with abundant myxoid stroma. We report a middle-aged man presenting with swelling on his hand for the last 11 years. He reports occasional pain in the swelling without any increase in its size or change of color. Radiologically, it mimicked a giant cell tumor of the tendon sheath. We received a white gelatinous tumor mass showing myxoid and hemorrhagic areas on cut section. Histo-morphological examinations suggested a diagnosis of EMC. Immunohistochemistry showed a strong expression of S100 and NSE. This slow-growing mass mimicking a benign giant cell tumor of tendon sheath warranted an urgent examination for metastasis and further treatment. Keywords: Chondrosarcoma, NR4A3 gene, Myxoid, pazopanib

Conflict of interest

The authors have nothing to disclose or any conflicts of interest.

Source of funding

None

How to cite: Sameen S et al. Extra Skeletal Myxoid Chondrosarcoma of Hand – A case Report with Review of Literature. Int J Histopathol 2022; 11(2):15-19. https://doi.org/10.56501/intjhistopatholinterpret.v11i2.521

Received: 15-08-2022; Accepted: 16-09-2022; Web Published: 26.09.2022