Review Article

Year : 2017| Volume : 2 | Issue : 2 | Page : 45-47

Merkel Cells: A Review on Role of Merkel Cells in Histology and Disease

Nandhini G. Ashok, Abilasha Ramasubramanian

Department of Oral Pathology, Saveetha Dental College, Chennai, Tamil Nadu, India

Address for correspondence:

Dr. Nandhini G. Ashok,

Department of Oral Pathology, Intern, Saveetha Dental College, Chennai ‐ 600 077, Tamil Nadu, India.

E‐mail: doc.nandhiniashok@gmail.com

Abstract

The basic objective of this review is to understand the role of Merkel cells (MCs). MCs are neuroendocrine cells present in the epidermis of basal layers of vertebrates. The origin of MCs is controversial. They act as mechanoreceptors. MC carcinoma is known to be aggravating primary cutaneous neoplasm. Diagnosis of this is based on their staining. Radiation therapy and chemotherapy are given for such patients.

Keywords: Merkel‐cell carcinoma, Merkel cells, neuroendocrine cells

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

How to cite this article: Ashok NG, Ramasubramanian A. Merkel cells: A review on role of merkel cells in histology and disease. Int J Orofac Res2017;2:45-7