Case Report

Year : 2022 | Volume : 5 | Issue : 2 | Page : 1-6

JIGSAW PUZZLE - A CLASSICAL DOSSIER OF PAGET’S DISEASE

Sandra Sagar 1 , Karthikeyan Ramalingam 2* , Pratibha Ramani 3

1Department of Oral & Maxillofacial Pathology, Saveetha Dental College & Hospitals, Chennai – 6000077 2* Professor and Head, Department of Oral & Maxillofacial Pathology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai – 6000077 3 Professor & Head, Department of Oral & Maxillofacial Pathology, Saveetha Dental College & Hospitals, Chennai – 6000077

Address for Correspondence:

Dr. Karthikeyan Ramalingam,

Associate Dean, Professor and Head,Department of Oral Pathology,Saveetha Dental College and Hospitals,

Saveetha Institute of Medical and Technical Sciences,Chennai, Tamilnadu, India.

Email:karthikeyanr.sdc@saveetha.com
Abstract

Paget’s disease (PD) is a chronic bone disease characterised by increased resorption followed by excessive bone formation resulting in bone pain and fractures. PD is most common in the elderly and many are initially asymptomatic but can develop severe complications as disease progresses. Serum alkaline phosphatase is an important biochemical marker which is elevated in these patients. A clinical lion like face and radiological “cotton wool appearance” and a “jigsaw puzzle” pattern on histopathological examination are the characteristic features of PD. Bisphosphonates are the most commonly used drug of choice for treatment of patients with Paget’s disease. We discuss a classic case of PD involving a 70 year old female in this case report.

Keywords:

Paget’s disease, Lion-like face, Cotton wool, Jigsaw puzzle

Financial support and sponsorship

Nil

Conflicts of interest

There are no conflicts of interest

How to cite this article: Sandra Sagar, Karthikeyan Ramalingam, & Pratibha Ramani. (2022). JIGSAW PUZZLE - A CLASSICAL DOSSIER OF PAGET’S DISEASE: Case Report. International Journal of Head and Neck Pathology, 5(2), 1–6. https://doi.org/10.56501/intjheadneckpathol.v5i2.554

Received :24/06/2022 Accepted: 15/07/2022 Web Published: 29/07/2022