Review Article

Year : 2021 | Volume : 9 | Issue : 2 | Page : 94 - 96

Biomagnification of Diseases: The Exposome Concept

Vijayashree Priyadharsini Jayaseelan, Arumugam Paramasivam

Clinical Genetics Lab, Cellular and Molecular Biology Centre, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences,

Saveetha University, Chennai, Tamil Nadu, India

Address for correspondence:

Dr. Vijayashree Priyadharsini Jayaseelan,

Clinical Genetics Lab, Cellular and Molecular Biology Centre, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Poonamallee High Road, Chennai ‐ 600 077, Tamil Nadu, India.

E‐mail: vijayashreej.sdc@saveetha.com

Abstract

The human race has gone through levels of destruction and extinctions happening for millions of years. Yet, the species tend to survive the most catastrophic situations presented before them. People have made their way into existence surpassing the mishaps simply quoted as “natural disasters.” However in recent times, humankind experiences a lot of annihilation due to “man‐made” factors that impose deleterious effects on health and the economy. Exposome refers to all the factors related to exposure which can influence the state of health or well being of an individual. Hence, exposome is a collective term that includes factors exposed by an individual, even before birth as a fetus and include sources from the environment, lifestyle, and occupation. The authors have made an attempt to address the consequences of exposome on human health and disease, relating it to the present pandemic situation. More studies pertaining to the gene‐environment interaction in different populations would provide insight into the development of diseases and evolutionary mechanisms conferring susceptibility or resistance to complex disease phenotypes.

Keywords: Exposure, phenotype, evolutionary mechanism

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

How to cite this article:

Jayaseelan VP, Paramasivam A. Biomagnification of diseases: The exposome concept. Int J Community

Dent 2021;9:94-6.